Vaccines : let the science speak !

The media inundates us with conflicting information about SARS-CoV-2 and its variants, about vaccines, about booster doses, about their safety, about their toxicity. What do we really know? Let’s take a look at some studies selected by Jean-Marc Sabatier.

But why does Emmanuel Macron want to “piss off” the non-vaccinated? Why this profusion of means to vaccinate the entire French population at all costs, including children?
The argument put forward by the health and political authorities is that the non-vaccinated present a danger for the rest of society. A sanitary danger first, because they will fill the hospitals and saturate the intensive care units. A social danger then, because they are bad citizens because they are resistant to the vaccine. They are therefore insubordinate and must be controlled.
The vaccine would give us the assurance of finally living normally, as we did before the pandemic, since it protects us, Macron, Castex, Véran, Attal, Blanquer, Delfraissy, Fischer and all the rest claim in chorus… The vaccine would be the weapon of mass destruction of the virus that must be imposed on everyone, at all costs!
Is this true? False? Let’s take a closer look at some scientific studies published in recent months. They have been selected by Jean-Marc Sabatier, Director of Research at the CNRS and Doctor in Cellular Biology and Microbiology.

1- Vaccination would (partially) protect against SARS-CoV-2 infection and Covid-19 diseases.

The mRNA 1273 vaccine is a lipid nanoparticle encapsulated mRNA vaccine that encodes the Spike protein. As soon as it was put on the market, the laboratories announced that it protected 94% of the disease. But successive waves of SARS-CoV-2 infections have been characterized by the evolution of highly mutated variants that are more transmissible and partially escape the adaptive immune response. Omicron is the fifth of these “variants of concern”.
The scientific justification for mandatory vaccination is based on the principle that vaccination prevents contamination of the vaccinated individual and transmission to others. However, studies (including in Israel) show that fully vaccinated individuals can transmit SARS-CoV-2 infection.
A recent investigation by the U.S. Centers for Disease Control and Prevention of an outbreak of COVID-19 in a Texas prison showed equal presence of the infectious virus in the nasopharynx of vaccinated and unvaccinated individuals.
Similarly, California researchers observed no major differences between vaccinated and unvaccinated individuals in terms of SARS-CoV-2 viral load in the nasopharynx, even in those with proven asymptomatic infection.
The current data therefore suggest that mandatory vaccination policies should be reconsidered.

Covid-19 : “Mass vaccination is inappropriate”

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2- People vaccinated against SARS-CoV-2 can be infected with the virus and its variants.

Yes, and we all know of people around us who have been vaccinated (two doses and a booster) and who have nevertheless caught Covid-19. Certainly without any serious form, but with all the symptoms of the disease.

Omicron: "la mauvaise nouvelle, c'est que c'est un variant qui infecte les gens qui sont vaccinés ou qui ont déjà eu le covid' affirme Catherine Hill, épidémiologiste pic.twitter.com/4hFGcbVCo8

— i24NEWS Français (@i24NEWS_FR) January 7, 2022

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3- People infected with SARS-CoV-2 can transmit the virus.

It is now known that any person, vaccinated or not, can transmit the virus. According to several studies, 30% of infected individuals never develop symptoms and are 75% as infectious as those who do. It also appears that 59% of all transmission would come from asymptomatic transmission.

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4- SARS-CoV-2 and antibody mediated infection (ADE)

All individuals have antibodies that neutralize viruses and antibodies that facilitate infection. This phenomenon is known by the abbreviation ADE (for “antibody-dependent enhancement”). It is these antibodies that must be avoided during vaccination, explain Jean-Marc Sabatier and Jacques Fantini, Professor of Biochemistry and Molecular Biology at the University of Aix-Marseille.
However, all current vaccines based on the Spike protein of SARS-CoV-2, produce these different types of antibodies. Hence the difficulties that we observe after the vaccination of certain patients. Hence also the worrying vaccine strategy of the 3ᵉ or 4ᵉ dose recommended, including in France, for patients with comorbidities (obesity, diabetes, hypertension, etc.).

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5- Vaccine efficacy decreases with the emergence of new SARS-CoV-2 variants.

The emergence of antibody-resistant SARS-CoV-2 variants may limit the therapeutic utility of monoclonal antibodies. Vaccine efficacy is highly dependent on the age of the patient.

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6- Existence of an escape phenomenon of SARS-CoV-2 variants to neutralizing antibodies directed against the viral spike protein.

The mRNA-based vaccines offer effective protection against the most common variants of SARS-CoV-2. However, some variants are completely immune to neutralizing antibodies. This is the case for the Omicron variant.

7- SARS-CoV-2 vaccines can potentially induce Covid-19 disease.

The binding of the coronavirus SARS-CoV-2 (or spike protein) to its cellular receptor ACE2 (angiotensin converting enzyme 2) interferes with the degradation of angiotensin 2 by ACE2 which, in excess, induces the over-activation of the cellular receptor AT1R. The over-activation of the RAS has very deleterious effects on the organism, leading in particular to the development of COVID-19 diseases. The AT1R receptor has vasoconstrictor (hypertensive), pro-inflammatory (cytokine storm), pro-thrombotic, pro-fibrosing, pro-oxidative (causes oxidative stress), pro-angiogenic, hypertrophying organs (heart, lungs, etc.), inhibiting the production of nitric oxide (NO) affecting the immune and nervous systems... The over-activated AT1R receptor (= RAS dysfunction) is thus the real culprit in Covid-19 diseases. — The binding of the coronavirus SARS-CoV-2 (or spike protein) to its cellular receptor ACE2 (angiotensin converting enzyme 2) interferes with the degradation of angiotensin 2 by ACE2 which, in excess, induces the over-activation of the cellular receptor AT1R. The over-activation of the RAS has very deleterious effects on the organism, leading in particular to the development of COVID-19 diseases.

As soon as the first vaccines were injected, side effects were observed in some patients. These side effects are infrequent and include venous thrombosis, stomach aches and headaches. More rare are the deaths observed shortly after the first injection. But they can also induce Covid-19 diseases: SARS-CoV-2 disrupts innate immunity, the menstrual cycle, affects renal, pulmonary and cardiovascular functions. But also the nervous functions, the intestinal microbiota.

And if the “SRA” explained the Covid-19?

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8- The effectiveness of vaccination against SARS-CoV-2 depends on the vitamin D status of the vaccinee.

It is widely demonstrated and we have written about it here several times, that vitamin D plays an essential role in the prevention of Covid-19 disease.

Vitamin D : the incredible French discoveries!

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9- Barrier measures (hand washing, distancing, wearing a mask) protect against contamination by SARS-CoV-2.

It is obvious, but it can never be said enough, the barrier gestures are the first ramparts against any form of transmission of pathogenic germs, including, obviously, the SARS-CoV-2 virus.